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Tuesday, September 29, 2020

STOPPING ANTI EPILEPTIC THERAPY : 6 PEARLS

  • Discontinued when children remain seizure free for at least 2 years
  • In benign epilepsy syndromes can be stopped after a period  as short as 6 months
  • Most relapses occur in the first 6 months
  • Most important risk factor for relapse following discontinuation is abnormal EEG before stopping drug  
  • Therapy should be discontinued slowly over a period of 3 to 6 months 
  • Most children who have not had a seizure for 2 yr or longer and who have a normal EEG when AED withdrawal is initiated remain free of seizures after discontinuing medication

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